Does local infiltration anaesthesia really provide longer analgesia than intrathecal morphine?
نویسندگان
چکیده
منابع مشابه
Postoperative pain relief after total hip arthroplasty: a randomized, double-blind comparison between intrathecal morphine and local infiltration analgesia.
BACKGROUND Postoperative pain after total hip arthroplasty (THA) can delay mobilization. This was assessed after intrathecal morphine (ITM) compared with local infiltration analgesia (LIA) using a non-inferiority design. METHODS Eighty patients were recruited in this randomized, double-blind study. ITM 0.1 mg (Group ITM) or periarticular local anaesthetic (ropivacaine 300 mg)+ketorolac 30 mg+...
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Glutamate signaling in the central nervous system is known to play a key role in pain regulation. AMPAkines can enhance glutamate signaling through α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. previous studies have shown that AMPAkines are effective analgesic agents, and their site of action is likely in the brain. It is not known, however, if AMPAkines can provide com...
متن کاملIntrathecal morphine reduces breakthrough pain during labour epidural analgesia.
BACKGROUND When using the combined spinal-epidural (CSE) technique for labour analgesia, parturients often experience breakthrough pain after the spinal medication has receded. We tested the hypothesis that a small dose of intrathecal morphine would reduce breakthrough pain. METHODS This was a randomized, double-blind, placebo-controlled trial. Subjects were randomized to receive either 100 m...
متن کاملOBSTETRICS Intrathecal morphine reduces breakthrough pain during labour epidural analgesia
Methods. This was a randomized, double-blind, placebo-controlled trial. Subjects were randomized to receive either 100 mg of morphine (MS) or placebo (PLCB) with the spinal injection of bupivacaine and fentanyl. Assessments included need for supplementation during labour analgesia, use of pain medications for 24 h after delivery, and side-effects. The primary endpoint was the rate of breakthrou...
متن کاملEpidural versus intrathecal morphine for postoperative analgesia after Caesarean section.
BACKGROUND Perispinal anaesthesia for Caesarean section allows injection of epidural (ED) or intrathecal (i.t.) morphine to provide long-lasting postoperative analgesia. To compare these two routes, a prospective, randomized, double-blinded study of 53 patients undergoing elective Caesarean section was performed. METHODS Combined spinal-epidural anaesthesia with 6 mg of i.t. hyperbaric bupiva...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2014
ISSN: 0007-0912
DOI: 10.1093/bja/aeu175